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綜合臨床實習(II) - 重症


1 Krüppel-like Factor 5 Mediates Proinflammatory Cytokine Expression in Lipopolysaccharide-induced Acute Lung Injury through Upregulation of Nuclear Factor-kappaB Phosphorylation in Vitro and in Vivo.
Chen HL, Chong IW, Lee YC, Tsai JR, Yuan SSF, Wang HM, Liu WL, Liu PL*
Mediators of inflammation (Manuscript number: 2014-281984 ; In Press)
(IF: 3.882; Ranking:74 /185=28.4%; Q2); Category: Cell Biology
SCI; Original articles
2 Percutaneous Dilatational Tracheostomy in Critically Ill Patients in Intensive Care Units.
Chang HL, Yang CJ, Hung JY, Hung CF, Su YC, Chong IW, Hwang JJ, Huang MS, Sheu CC,Tsai JR
J Intern Med Taiwan 2013; 24: 153-161
ISI: Original articles
3 Right ptosis, anhidrosis, and miosis developed in a 49-year-old man with chronic dry cough for 2 months.
Yang CJ, Lee JY, Wu CC, Tsai JR, Chou SH, Huang MS*.
Chest. 2012 Jul;142(1):246-51.
(IF: 5.25; ranking: 4/48= 8.3%; Q1); Category: Respiratory system
SCI; Case report; PMID: 22796847.
4 Pemetrexed as a Possible Cause of Severe Rhabdomyolysis in the Treatment of Lung Cancer.
Huang MS, Tsai JR, Shen MC, Chou SH, Yang CJ*
Lung Cancer. 2012 Jun;76(3):491-2. 
(IF: 3.434; ranking: 11/48= 22.9%; Q1); Category: Respiratory system
SCI; Case report; PMID: 22405568.
5 Inadequate Energy Delivery During Early Critical Illness Correlates with Increased Risk of Mortality in Patients who Survive at Least Seven Days: a Retrospective Study.
Tsai JR, Chang WT, Sheu CC, Wu YJ, Sheu YH, Liu PL, Ker CG, Huang MC*.
Clin Nutr. 2011 Apr;30(2):209-14.
(IF= 3.41 Rinking:15/ 70=21.428%; Q1); Category: Nutrition & Dietetics
SCI: Original articles; PMID
6 Small Intestine Intussusceptions Secondary to Metastasis from Adenocarcinoma of The Lung.
Cheng JY, Yang CJ, Tsai JR, Chai CY, Huang WT, Wang JY, Hwang JJ, Huang MS 
Thorac Med 2011; 26: 160-164
ISSN: Case Report
7 Tsai JR , Chang WT, Sheu CC, Wu YJ, Sheu SH , Liu PL, Ker CG, Huang MC. Inadequate energy delivery during early critical illness correlates with increased risk of mortality in patients who survive at least seven days: A retrospective study. Clin Nutr. 2010 Oct 11.
8 Liu PL, Tsai JR, Chiu CC, Hwang JJ, Chou SH, Wang CK, Wu SJ, Chen YL, Chen WC, Chen YH, Chong IW. Decreased expression of thrombomodulin is correlated with tumor cell invasiveness and poor prognosis in nonsmall cell lung cancer. Mol Carcinog. 2010 Oct;49(10):874-81 (SCI)
9 Liu PL, Tsai JR, Charles AL, Hwang JJ, Chou SH, Ping YH, Lin FY, Chen YL, Hung CY, Chen WC, Chen YH, Chong IW Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases. Mol Nutr Food Res. 2010 Jul;54 Suppl 2:S196-204 (SCI)
10 Chen CC, Chiu HH, Yen LC, Chang HJ, Chang MS, Tsai JR, Chen YF, Lin SR. Overexpression of EGFR pathway-related genes in the circulation is highly correlated with EGFR mutations and overexpression in paired cancer tissue from patients with non-small cell lung cancer. Oncol Rep. 2010 Mar;23(3):639-45 (SCI)
11 Wang CY, Lin KH, Yang CJ, Tsai JR, Hung JY, Wang PH, Hsu HK, Huang MS. Toona sinensis extracts induced cell cycle arrest and apoptosis in the human lung large cell carcinoma.Kaohsiung J Med Sci. 2010 Feb;26(2):68-75
12 Su SH, Tsai WC, Lin CY, Lin WR, Chen TC, Lu PL, Huang PM, Tsai JR, Wang YL, Feng MC, Wang TP, Chen YH. Clinical features and outcomes of spinal tuberculosis in southern Taiwan. J Microbiol Immunol Infect. 2010 Aug;43(4):291-300. (SCI)
13 Tsai MJ, Lien CT, Chang WA, Wei PJ, Hsieh MH, Tsai YM, Tsai JR, Huang MS Transperineal ultrasonography in the diagnosis of Fournier's gangrene. Ultrasound Obstet Gynecol. 2010 Sep;36(3):389-90 (SCI)
14 Liu PL, Tsai JR, Hwang JJ, Chou SH, Cheng YJ, Lin FY, Chen YL, Hung CY, Chen WC, Chen YH, Chong IW. High Mobility Group Box 1-Mediated Matrix Metalloproteinase-9 Expression in Non-Small Cell Lung Cancer Contributes to Tumor Cell Invasiveness. American Journal of Respiratory Cell and Molecular Biology 2009 Nov 20. [Epub ahead of print] ?(SCI)
15 Chang MY, Yu YP, Tsai JR, Sheu CC, Chong IW, Lin SR.Combined oligonucleotide microarray-bioinformatics and constructed membrane arrays to analyze the biological pathways in the carcinogenesis of human lung adenocarcinoma. Oncol Rep2007 Sep;18(3):569-79 ?(SCI)
16 Tsai JR , Chong IW, Chen YH, Yang MJ, Sheu CC, Chang HC, Hwang JJ, Hung JY, Lin SR. Differential Expression Profile of MAGE Family in Non-Small Cell Lung Cancer. Lung Cancer. (2007;56(2): 185-92 (SCI)
17 Sheu CC, Tsai JR, Hung JY,? Yang CJ,1 Hung HC, Chong IW, Huang MS,and? Hwang JJ. Admission time and outcomes of patients in a medical intensive care unit Kaohsiung Journal of Medical Sciences 2007; 23:396-405
18 Sheu CC, Tsai JR, Hung JY, Cheng MH, Chong IW, Hwang JJ, Huang MS A simple modification of ciaglia blue rhino technique for tracheostomy: using a guidewire dilating forceps ofr initial dilation. EUR J Cardiothorac Surg. 2007; 31(1):114-119(SCI)
19 Chih-Jen Yang, Ming-Shyan Huang, Jhi-Jhu Hwang, Tun-Chieh Chen, Po-Liang Lu, Inn-Wen Chong, Chau-Chyun Sheu, Jong-Rung Tsai, Jen-Yu Hung. Routine Culture for Mycobacterium Tuberculosis from Bronchoscopy in Taiwan ?Respirology.2007; 12(3):412-5 (SCI)
20 Chih-Jen Yang, Jhi-Jhu Hwang, Wang-Yi Kang, Inn-Wen Chong, Tung-Heng Wang, Chau-Chun Sheu, Jong-Rung Tsai, Ming-Shyan Huang ?Gastro-Intestinal Metastasis of Primary Lung Carcinoma Clinical Presentations and Outcome. Lung Cancer 2006; 54:319-323 (SCI)
21 Jong-Rung Tsai, Chau-Chyun Sheu, Meng-Hsuan Cheng, Jen-Yu Hung, Chuan-Sheng Wang, Inn-Wen Chong, Ming-Shyang Huang and Jhi-Jhu Hwang Organophosphate poisoning: 10 years of experience in Southern Taiwan Kaohsiung Journal of Medical Science 2007; 23(3):108-15
22 Sheu CC, Tsai JR, Cheng MH, Chong IW, Huang MS, Hwang JJ. (2006) Safety of performing percutaneous dilational tracheostomy in patients with preexisting barotrauma. KaohsiungJournal of Medical Science 2006; Nov;22(11):570-574
23 Inn-Wen Chong, Mei-Yin Chang, Huang-Chou Chang, Ya-Ping Yu, Chau-Chyun Sheu, Jong-Rung Tsai, Jen-Yu Hung, Shah-Hwa Chou, Mee-Sun Tsai, Jhi-Jhu Hwang and Shiu-Ru Lin (2006) Great potential of a panel of multiple hMTH1, SPD, ITGA11 and COL11A1 markers for diagnosis of patients with non-small cell lung cancer. Oncology Reports 16(5)981-988 (SCI)
24 Chau-Chyun Sheu, Jong-Rung Tsai, Inn-Wen Chong, Jhi-Jhu Hwang (2006) Nutritional emphysema. Internal Medicine Journal (25)0,312-322 (SCI)
25 Sheu CC, Chang MY, Chang HC, Tsai JR, Lin SR, Chang SJ, Hwang JJ, Huang MS, Chong IW. (2006)Combined detection of CEA, CK-19 and c-met mRNAs in peripheral blood: a highly sensitive panel for potential molecular diagnosis of non-small cell lung cancer. Oncology Basel 2006 70(3): 203-211; (SCI)
26 Jong-Rung Tsai , Inn-Wen Chong, Chung-Chi Chen, Shiu-Ru Lin, Chau-Chyun Sheu and Jhi-Jhu Hwang . (2006)Mitogen-activated protein kinase pathway was significantly activated in human bronchial epithelial cells by nicotine. DNA and Cell Biology 200625(5): 312-322 (SCI)
27 Chau-Chyun Sheu, Yu YP, Tsai JR, Chang MY, Lin SR, Jhi-Jhu Hwang and Chong IW*. (2006)Development of a membrane array-based multimarker assay for detection of circulating cancer cells in patients with non-small cell lung cancer. International Journal of Cancer2006(119)1419-1426 (SCI)
28 Chau-Chyun Sheu, Jhi-Jhu Hwang, Jong-Rung Tsai, Tung-Heng Wang, Inn-Wen Chong, Ming-Shyan Huang*. (2006)Spontaneous Pneumothorax as a Complication of Septic Pulmonary Embolism in an IV Drug User The Kaohsiung Journal of Medical Sciences2006:22(2)89-93
29 Wen-Yu Wang, Tung-Heng Wang, Chuan-Sheng Wang, Jong-Rung Tsai, Chau-Chyun Sheu, Jen-Yu Hung, Te-Hung Hsu, Ming-Shyan Huang(2005)The Changes of ?Protein kinases C in Rat Alveolar Macrophages during Sepsis. Thorac Med20(5)354-361
30 Meng-Hsuan Cheng, Jong-Rung Tsai, Chau-Chyun Sheu, Jen-Yu Hung, Te-Hung Hsu, Ming-Shyan Huang.(2003) Cardiac Tamponade Due to Pneumopericardium--A Case Report.Thorac Med.18(6)513-518.
31 Chuan-Sheng Wang, Kun-Bow Tsai, Jong-Rung Tsai, Chau-Chyun Sheu, Jen-Yu Hung, Te-Hung Hsu, Ming-Shyan Huang..(2003)Primary Lymphoepithelioma-Like Carcinoma of Lung Associated with Hypertrophic Osteoarthropathy- A Case Report. Thorac Med.18(5)455-460.
32 Chuan-Sheng Wang, Kun-Bow Tsai, Jong-Rung Tsai, Chau-Chyun Sheu, Jen-Yu Hung, Te-Hung Hsu and Ming-Shyang Huang. (2003) Primary Malignant Fibrous Histiocytoma of the Lung: A Case Report. Kaohsiung J Med Sci 19(8)428-432
33 Chau-Chyun Sheu, Tung-Heng Wang, Jhi-Jhu Hwang, Inn-Wen Chong, Te-Hung Hsu, Jong-Rung Tsai, Jen-Yu Hung, Li-Tzong Chen, Ching-Hsun Liu, Kun-Pao Tsai, Ming-Shyan Huang (2002) High-grade Bronchial Mucoepidermoid Carcinoma- A Case Report. Thoracic Medicine17(2):165~171
34 Jong-Rung Tsai , Chau-Chyun Sheu, Jen-Yu Hung, Te-Hung Hsu, Kun-Bow Tsai, Ming-Shyan Huang (2002) Multiple Intrapulmonary Metastases of Atypical Bronchial Carcinoid Tumor-A Case Report and Literature Review. Thoracic Medicine 17(2):159~164
35 Jong-Rung Tsai , Inn-Wen Chong, Jen-Yu Hung, and Kun-Bow Tsai. (2002) Use of Urine Pregnancy Test for Rapid Diagnosis of Primary Pulmonary Choriocarcinoma in a Man. Chest121: 996-998, 2002. (SCI)



序號 計畫名稱及編號 補助單位 執行期限
1 脂泌素在人類非小細胞肺癌轉移之角色與薑黃素抗癌效果之探討 (NSC 100-2320-B-037-012-MY2) 國科會專題研究計畫
2011/08/01 ~ 2013/07/31
2 探討厚朴酚(Magnolol)誘發肺癌細胞凋亡之相關路徑與機轉 (KMUH 99-9M64) 高雄醫學大學附設中和紀念醫院指導型計畫 2011/02/01 ~ 2012/01/31
3 熱休克蛋白27在銀杏萃取物抑制人類肺癌細胞增生與侵犯的角色 (KMU-Q099022) 高醫新進教師研究計畫 2010/02/10 ~
4 人類凝血?調節素蛋白、高遷移率族蛋白B1在非小細胞肺癌轉移之角色與甘草酸?抗癌效果之探討(NSC95-2314-13-037-015) 國科會專題研究計畫
2006/08/01 ~ 2007/07/31
5 研究PPM1d基因於肺癌之分子致病機轉 
2005/08/01 ~ 2006/07/31

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